Dragon Quest II HD-2D Remake Guide | How to Cure All Status Effects
Here's a guide on how to cure all Status Effects in Dragon Quest II HD-2D Remake.
Game Guide by Ragib Rawnak on Nov 14, 2025
This guide explains all status effects in the Dragon Quest 2 HD-2D Remake, how each ailment functions, and the methods you can use to cure or prevent them. The information below will help you manage conditions during battles and when exploring.

Sleep Status Effect
If your character is affected by Sleep, they cannot take any action until the effect ends. They will eventually wake up after several turns. Your character can also wake up if a physical attack hits them, but this cannot be relied on since the enemy may target someone else or use a spell instead.
Poison Status Effect
Your character under Poison is unable to cast spells. Any attempt to cast one will cause them to lose the turn without producing an effect in Dragon Quest II HD-2D Remake.
Dazzle Status Effect
The Dazzle ailment prevents your character from casting spells, and any attempt to do so will result in a wasted turn.

Fizzle Status Effect
The Fizzle status seals your character’s spellcasting. They will fail any spell they try to cast and lose their action for that turn.
Curse Status Effect
The effect of the Curse depends on the specific cursed equipment being used. Cursed gear cannot be removed manually, so you must rely on other methods to clear the condition in Dragon Quest II HD-2D Remake.
Preventing Status Ailments With Fizzle
Casting Fizzle is a way to stop enemy spellcasters from applying status conditions. The spell costs 5 MP and seals the spells of one group of enemies.
While Fizzle does not remove existing ailments, using it early can prevent many conditions from being inflicted if the enemy is susceptible to it.

Managing Sleep During Battle
If Sleep affects your character, they will wake up on their own after a few turns. They might also wake up if they are physically hit, but this isn't always the case, as enemies may hit you with alternative methods. You can't defend yourself or help in the fight until the effect goes off.
Removing Ailments at a Church
You can remove Poison and Curse by visiting a Priest or Nun. They can clear these conditions in exchange for gold. Ensure you have sufficient funds before requesting their assistance.
Preventing Ailments Through Equipment
Some equipment pieces increase resistance to status conditions. The Banishing Bells help resist Snooze and Fizzle, while the Fizzle-Retardant Blouse prevents spell sealing. The Necklace of Immunity helps reduce the chance of being poisoned.
The Torc of Truth lowers the chance of being affected by Dazzle, and the Full Moon Ring reduces the chance of paralysis. By equipping these items, you lower your risk of being affected during combat in Dragon Quest II HD-2D Remake.

Removing Poison With Squelch or Herbs
To cure Poison, you can cast Squelch or use an Antidotal Herb. Using an herb is often preferred, as it allows you to save MP for other needs later in the fight or while exploring.
Also, check our Dragon Quest I & II: HD-2D Remake Review and other guides below:
- Dragon Quest I HD-2D Remake Guide | How to Cross Damaging Floor Tiles
- Dragon Quest I HD-2D Remake Guide | How to do Critical Hits
- Dragon Quest I HD-2D Remake Guide | All Bank Locations
- Dragon Quest I HD-2D Remake Guide | How to Remove Cursed Equipment
- Dragon Quest I HD-2D Remake Guide | How to Get Erdrick's Equipment Set
- Dragon Quest I HD-2D Remake Guide | How to Beat Knight Errant Boss
- Dragon Quest I HD-2D Remake Guide | How to Beat Knight Aberrant Boss
- Dragon Quest I HD-2D Remake Guide | How to Beat Spiketail Boss
- Dragon Quest I HD-2D Remake Guide | How to Beat Mirage Boss
- Dragon Quest I HD-2D Remake Guide | How to Beat Golem Boss
- Dragon Quest I HD-2D Remake Guide | How to Beat Green Dragon Boss
- Dragon Quest I HD-2D Remake Guide | How to Beat the Sorcerer Boss
- Dragon Quest I HD-2D Remake Guide | How to Beat Robbin Ood Boss
- Dragon Quest I HD-2D Remake Guide | How to Find All Zalen Sidequests
- Dragon Quest I HD-2D Remake Guide | How to Craft Items
- Dragon Quest I HD-2D Remake Guide | How to Find All Keys
- Dragon Quest I HD-2D Remake Guide | How to Farm Metal Slime
- Dragon Quest I HD-2D Remake Guide | How to Rescue Princess Gwaelin
- Dragon Quest I HD-2D Remake Guide | All Character Stats
- Dragon Quest II HD-2D Remake Guide | How to Use All Keys
- Dragon Quest II HD-2D Remake Guide | How to Remove Cursed Equipment
- Dragon Quest II HD-2D Remake Guide | How to Use Banks
- Dragon Quest II HD-2D Remake Guide | How to Farm Metal Slime
- Dragon Quest II HD-2D Remake Guide | How to Play Tombola
- Dragon Quest II HD-2D Remake Guide | How to Cross Damaging Floor Tiles
- Dragon Quest II HD-2D Remake Guide | All Erdrick’s Equipment Set Location
- Dragon Quest II HD-2D Remake Guide | How to Unlock the Ship
- Dragon Quest II HD-2D Remake Guide | How to Revive Party Members
- Dragon Quest II HD-2D Remake Guide | How to Use Stat Seeds
- Dragon Quest II HD-2D Remake Guide | All Stat Seeds Buffs
- Dragon Quest II HD-2D Remake Guide | How to Upgrade Equipment
- Dragon Quest II HD-2D Remake Guide | How to Farm Gold
- Dragon Quest II HD-2D Remake Guide | How to Find All Keys
- Dragon Quest II HD-2D Remake Guide | How to Farm XP and Level Up
- Dragon Quest II HD-2D Remake Guide | How to Transfer Items
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